Ethylhexyl Gallate

INCI: ETHYLHEXYL GALLATE

CAS Number
1034-01-1 (octyl gallate; E 311 food additive designation)
Function
Antioxidant
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” octyl gallate is GRAS for food use (21 CFR 184); no specific cosmetic restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Known contact sensitiser routinely tested in epicutaneous patch test series by dermatologists with cross-reactivity to propyl gallate and dodecyl gallate; use low concentrations and consider HRIPT testing for leave-on products.

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Concern Level: Moderate

Frequently Asked Questions

Is Ethylhexyl Gallate safe in cosmetics?

Known contact sensitiser routinely tested in epicutaneous patch test series by dermatologists with cross-reactivity to propyl gallate and dodecyl gallate; use low concentrations and consider HRIPT testing for leave-on products. The EU classifies Ethylhexyl Gallate as "restricted". Safety rating: MODERATE.

Is Ethylhexyl Gallate allowed in the EU?

Ethylhexyl Gallate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ethylhexyl Gallate do in cosmetics?

Ethylhexyl Gallate functions as: Antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 1034-01-1 (octyl gallate; E 311 food additive designation).

What is the Margin of Safety for Ethylhexyl Gallate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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