Regulatory Status
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Safety Data
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Expert Verdict
Euonymus japonicus leaf extract contains potential cardiotoxic sesquiterpene alkaloids (evonine, evonoside, evomonoside) and cardiac glycosides; analytical verification of alkaloid absence is mandatory before cosmetic use, with comprehensive chemical characterization and targeted alkaloid screening required for CPSR due to very limited safety literature and lack of CIR or SCCS opinion.
Regulatory Flags
Frequently Asked Questions
Is Euonymus Japonicus Leaf Extract safe in cosmetics?
Euonymus japonicus leaf extract contains potential cardiotoxic sesquiterpene alkaloids (evonine, evonoside, evomonoside) and cardiac glycosides; analytical verification of alkaloid absence is mandatory before cosmetic use, with comprehensive chemical characterization and targeted alkaloid screening required for CPSR due to very limited safety literature and lack of CIR or SCCS opinion. The EU classifies Euonymus Japonicus Leaf Extract as "permitted". Safety rating: MODERATE.
Is Euonymus Japonicus Leaf Extract allowed in the EU?
Euonymus Japonicus Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Euonymus Japonicus Leaf Extract do in cosmetics?
Euonymus Japonicus Leaf Extract functions as: Eugenyl acetate. It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned (botanical extract).
What is the Margin of Safety for Euonymus Japonicus Leaf Extract?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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