Eupatorium Perfoliatum Extract

INCI: EUPATORIUM PERFOLIATUM EXTRACT

CAS Number
84625-35-4
Function
Skin Conditioning, Anti-inflammatory
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No explicit FDA restriction; EWG does not list it as unacceptable; however pyrrolizidine alkaloid content warrants precautionary use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contains dehydropyrrolizidine alkaloids (lycopsamine, intermedine) linked to hepatotoxicity at chronic low-level exposure; suitable for short-contact use only with caution; not recommended for damaged skin

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Concern Level: Moderate

Regulatory Flags

pyrrolizidine-alkaloids hepatotoxin-risk precautionary

Frequently Asked Questions

Is Eupatorium Perfoliatum Extract safe in cosmetics?

Contains dehydropyrrolizidine alkaloids (lycopsamine, intermedine) linked to hepatotoxicity at chronic low-level exposure; suitable for short-contact use only with caution; not recommended for damaged skin The EU classifies Eupatorium Perfoliatum Extract as "permitted". Safety rating: MODERATE.

Is Eupatorium Perfoliatum Extract allowed in the EU?

Eupatorium Perfoliatum Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Eupatorium Perfoliatum Extract do in cosmetics?

Eupatorium Perfoliatum Extract functions as: Skin Conditioning, Anti-inflammatory. It is classified as a cosmetic ingredient in our database. CAS number: 84625-35-4.

What is the Margin of Safety for Eupatorium Perfoliatum Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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