Glaucine

INCI: GLAUCINE

CAS Number
475-81-0
Function
Skin conditioning, anti-inflammatory, lipolytic
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No FDA restrictions; used in anti-cellulite and slimming cosmetics

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Well-regarded aporphine alkaloid from Glaucium flavum with PDE4 inhibition, anti-inflammatory, and lipolytic properties; used in anti-cellulite and firming products; good safety profile for topical application

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Concern Level: Low

Regulatory Flags

plant-derived alkaloid anti-cellulite pde4-inhibitor

Frequently Asked Questions

Is Glaucine safe in cosmetics?

Well-regarded aporphine alkaloid from Glaucium flavum with PDE4 inhibition, anti-inflammatory, and lipolytic properties; used in anti-cellulite and firming products; good safety profile for topical application The EU classifies Glaucine as "permitted". Safety rating: GOOD.

Is Glaucine allowed in the EU?

Glaucine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Glaucine do in cosmetics?

Glaucine functions as: Skin conditioning, anti-inflammatory, lipolytic. It is classified as a cosmetic ingredient in our database. CAS number: 475-81-0.

What is the Margin of Safety for Glaucine?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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