Is Glaucine safe in cosmetics?
Glaucine has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Glaucine
Also known as: Boldine dimethyl ether, Bromcholitin, EINECS 207-501-5, S-(+)-Glaucine, Glauvent (+4 more)
INCI: GLAUCINE
Glaucine (CAS 475-81-0) is a cosmetic cosmetic ingredient functioning as Skin conditioning, anti-inflammatory, lipolytic. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 475-81-0 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning, anti-inflammatory, lipolytic
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
(6aS)-1,2,9,10-tetramethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
InChIKey
RUZIUYOSRDWYQF-HNNXBMFYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No FDA restrictions; used in anti-cellulite and slimming cosmetics
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Glaucine.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Glaucine.
Regulatory Flags
plant-derived
alkaloid
anti-cellulite
pde4-inhibitor
Known Synonyms
Boldine dimethyl ether
Bromcholitin
EINECS 207-501-5
S-(+)-Glaucine
Glauvent
NSC 34396
(S)-5,6,6a7-Tetrahydro-1,2,9,10-tetramethoxy-6-methyl-4H-dibenzo(de,g)quinoline
1,2,9,10-Tetramethoxy-6a-alpha-aporphine
UNII-NU19306XA7
Chemical Function
Softener and conditioner
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
GLAUCINE
ChEMBL ID
CHEMBL228082
Frequently Asked Questions
Is Glaucine allowed in the EU?
Glaucine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Glaucine do in cosmetics?
Glaucine functions as: Skin conditioning, anti-inflammatory, lipolytic. It is classified as a cosmetic ingredient in our database. CAS number: 475-81-0.
Is Glaucine used outside cosmetics?
Glaucine also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Glaucine compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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