Excellent UV Filter / Sunscreen

GLUCOMANNAN

CAS Number
76081-94-2
Function
Humectant, viscosity control agent
Safety Rating
EXCELLENT

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes GRAS (Generally Recognized as Safe); GRN No. 407. FDA determined glucomannan qualifies as dietary fiber (January 2020). Not listed as prohibited or restricted under 21 CFR 700. EPA exemption from pesticide tolerance requirements established 2018 (CAS 37220-17-0).

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

GLUCOMANNAN is a water-soluble polysaccharide derived from Amorphophallus konjac root, permitted without restriction under EU Regulation (EC) No. 1223/2009. The CIR Expert Panel (2015) concluded it is safe in present practices of use and concentration; EFSA (2017) found no safety concern. Its high molecular weight (200,000-2,000,000 Da) precludes meaningful dermal absorption, genotoxicity is negative across all assays, and historical respiratory sensitization concerns have been definitively attributed to a protein contaminant, not glucomannan itself.

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Concern Level: None

Regulatory Flags

eu-unrestricted cir-approved no-sccs-opinion gras-fda natural-origin

Frequently Asked Questions

Is GLUCOMANNAN safe in cosmetics?

GLUCOMANNAN is a water-soluble polysaccharide derived from Amorphophallus konjac root, permitted without restriction under EU Regulation (EC) No. 1223/2009. The CIR Expert Panel (2015) concluded it is safe in present practices of use and concentration; EFSA (2017) found no safety concern. Its high molecular weight (200,000-2,000,000 Da) precludes meaningful dermal absorption, genotoxicity is negative across all assays, and historical respiratory sensitization concerns have been definitively attributed to a protein contaminant, not glucomannan itself. The EU classifies GLUCOMANNAN as "permitted". Safety rating: EXCELLENT.

Is GLUCOMANNAN allowed in the EU?

GLUCOMANNAN EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does GLUCOMANNAN do in cosmetics?

GLUCOMANNAN functions as: Humectant, viscosity control agent. It is classified as a UV Filter / Sunscreen in our database. CAS number: 76081-94-2.

What is the Margin of Safety for GLUCOMANNAN?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check GLUCOMANNAN compliance across multiple jurisdictions:

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Ingredient Decoder
Paste a full ingredient list for instant analysis
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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