Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Glutamine. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 3379 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| dose_tested | 3379 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
Expert Verdict
EXCELLENT safety profile. No carcinogenicity classification. Not a skin or eye irritant. Ensure appropriate preservation in aqueous formulations due to microbial susceptibility.
Regulatory Flags
Frequently Asked Questions
Is Glutamine safe in cosmetics?
EXCELLENT safety profile. No carcinogenicity classification. Not a skin or eye irritant. Ensure appropriate preservation in aqueous formulations due to microbial susceptibility. The EU classifies Glutamine as "permitted". Safety rating: EXCELLENT. 2 toxicological study endpoint(s) are available in our database.
Is Glutamine allowed in the EU?
Glutamine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Glutamine do in cosmetics?
Glutamine functions as: Hair conditioning / skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 56-85-9.
What is the Margin of Safety for Glutamine?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Glutamine?
The NOAEL (No Observed Adverse Effect Level) for Glutamine is 3379 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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