Glycereth-18

INCI: GLYCERETH-18

CAS Number
31694-55-0 (generic)
Function
Skin-conditioning agent (humectant)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” CIR concluded safe as used when formulated to be non-irritating (Dec 2020); max use 0.3% leave-on, 0.32% rinse-off

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

1,4-dioxane and ethylene oxide impurity control required; used in bath soaps at โ‰ค0.3% and mucous membrane products; reported in 21 formulations (VCRP 2020)

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Concern Level: Low

Frequently Asked Questions

Is Glycereth-18 safe in cosmetics?

1,4-dioxane and ethylene oxide impurity control required; used in bath soaps at โ‰ค0.3% and mucous membrane products; reported in 21 formulations (VCRP 2020) The EU classifies Glycereth-18 as "permitted". Safety rating: GOOD.

Is Glycereth-18 allowed in the EU?

Glycereth-18 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Glycereth-18 do in cosmetics?

Glycereth-18 functions as: Skin-conditioning agent (humectant). It is classified as a cosmetic ingredient in our database. CAS number: 31694-55-0 (generic).

What is the Margin of Safety for Glycereth-18?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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