Glycidoxypropyl Polysilsesquioxane

INCI: GLYCIDOXYPROPYL POLYSILSESQUIOXANE

CAS Number
Not assigned (polysilsesquioxane polymer)
Function
Film former, nail conditioning agent
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” CIR Expert Panel reviewed 18 polysilsesquioxanes and concluded safe in present practices of use and concentration

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Inhalation exposure from powder products flagged by CIR, but particles from cosmetics deemed not respirable to any appreciable amount. Epoxide group consumed during polymerization; residual levels expected to be extremely low.

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Concern Level: Low

Frequently Asked Questions

Is Glycidoxypropyl Polysilsesquioxane safe in cosmetics?

Inhalation exposure from powder products flagged by CIR, but particles from cosmetics deemed not respirable to any appreciable amount. Epoxide group consumed during polymerization; residual levels expected to be extremely low. The EU classifies Glycidoxypropyl Polysilsesquioxane as "permitted". Safety rating: GOOD.

Is Glycidoxypropyl Polysilsesquioxane allowed in the EU?

Glycidoxypropyl Polysilsesquioxane EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Glycidoxypropyl Polysilsesquioxane do in cosmetics?

Glycidoxypropyl Polysilsesquioxane functions as: Film former, nail conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (polysilsesquioxane polymer).

What is the Margin of Safety for Glycidoxypropyl Polysilsesquioxane?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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Is Glycidoxypropyl Polysilsesquioxane in Your Products?

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