Moderate Cosmetic Ingredient Sensitization Data

Grindelia Robusta Extract

INCI: GRINDELIA ROBUSTA EXTRACT

CAS Number
84696-17-3
Function
Skin conditioning, tonic
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted. Grindelia is recognized in the US Pharmacopeia for traditional use; no specific FDA cosmetic prohibition.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Sensitization Profile

Contact sensitization data for Grindelia Robusta Extract based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
botanical
EU Allergen Listed
no
Patch Test Positive Rate
0.3%
Cross-reactivity Group
compositae-group
Reaction Type
contact-dermatitis

Source: IVDK; literature review

Expert Verdict

Compositae allergy risk exists due to resin content; high concentrations may cause skin irritation. Limited safety data with no CIR or SCCS review; manufacturer must conduct safety assessment per Article 10 of EC 1223/2009. Pesticide residue testing recommended for wild-harvested material.

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Concern Level: Moderate

Regulatory Flags

plant-extract natural-origin

Frequently Asked Questions

Is Grindelia Robusta Extract safe in cosmetics?

Compositae allergy risk exists due to resin content; high concentrations may cause skin irritation. Limited safety data with no CIR or SCCS review; manufacturer must conduct safety assessment per Article 10 of EC 1223/2009. Pesticide residue testing recommended for wild-harvested material. The EU classifies Grindelia Robusta Extract as "permitted". Safety rating: MODERATE.

Is Grindelia Robusta Extract allowed in the EU?

Grindelia Robusta Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Grindelia Robusta Extract do in cosmetics?

Grindelia Robusta Extract functions as: Skin conditioning, tonic. It is classified as a cosmetic ingredient in our database. CAS number: 84696-17-3.

What is the Margin of Safety for Grindelia Robusta Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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