Caffeine Carboxyloyl SH-Decapeptide-1

INCI: CAFFEINE CARBOXYLOYL SH-DECAPEPTIDE-1

CAS Number
Not assigned (novel peptide conjugate)
Function
Skin Conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not established โ€” supplier dossier mandatory

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Novel ingredient with synthetic human-identical peptide sequence; no independent published safety studies; full reliance on supplier toxicology package required.

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Concern Level: High

Frequently Asked Questions

Is Caffeine Carboxyloyl SH-Decapeptide-1 safe in cosmetics?

Novel ingredient with synthetic human-identical peptide sequence; no independent published safety studies; full reliance on supplier toxicology package required. The EU classifies Caffeine Carboxyloyl SH-Decapeptide-1 as "permitted". Safety rating: MODERATE.

Is Caffeine Carboxyloyl SH-Decapeptide-1 allowed in the EU?

Caffeine Carboxyloyl SH-Decapeptide-1 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Caffeine Carboxyloyl SH-Decapeptide-1 do in cosmetics?

Caffeine Carboxyloyl SH-Decapeptide-1 functions as: Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (novel peptide conjugate).

What is the Margin of Safety for Caffeine Carboxyloyl SH-Decapeptide-1?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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