Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Gum Arabic (Acacia Senegal Gum). NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 1600 mg/kg bw/day | oral | mouse | Developmental | COSMOS_DB |
| NOAEL | 1600 mg/kg bw/day | oral | rat | Developmental | COSMOS_DB |
| NOAEL | 1600 mg/kg bw/day | oral | hamster | Developmental | COSMOS_DB |
| NOAEL | 800 mg/kg bw/day | oral | rabbit | Developmental | COSMOS_DB |
| NOAEL | 30000 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 10000 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 15000 mg/kg bw/day | oral | mouse | Short Term Toxicity | COSMOS_DB |
| NOAEL | 10000 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 15000 mg/kg bw/day | oral | mouse | Subchronic | COSMOS_DB |
| NOAEL | 5000 mg/kg bw/day | oral | rat | Carcinogenicity | COSMOS_DB |
Expert Verdict
Potential dermal and respiratory sensitizer per EFSA feed additive opinion; occupational inhalation is the primary risk, not dermal application
Regulatory Flags
Frequently Asked Questions
Is Gum Arabic (Acacia Senegal Gum) safe in cosmetics?
Potential dermal and respiratory sensitizer per EFSA feed additive opinion; occupational inhalation is the primary risk, not dermal application The EU classifies Gum Arabic (Acacia Senegal Gum) as "permitted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database.
Is Gum Arabic (Acacia Senegal Gum) allowed in the EU?
Gum Arabic (Acacia Senegal Gum) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Gum Arabic (Acacia Senegal Gum) do in cosmetics?
Gum Arabic (Acacia Senegal Gum) functions as: Viscosity controlling, film forming, emulsion stabilizing, binding. It is classified as a cosmetic ingredient in our database. CAS number: 9000-01-5.
What is the Margin of Safety for Gum Arabic (Acacia Senegal Gum)?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Gum Arabic (Acacia Senegal Gum)?
The NOAEL (No Observed Adverse Effect Level) for Gum Arabic (Acacia Senegal Gum) is 1600 mg/kg bw/day based on a Developmental study via oral route in mouse. A total of 10 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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