Gymnema Sylvestre Stem Extract

INCI: GYMNEMA SYLVESTRE STEM EXTRACT

CAS Number
Not specifically assigned (parent: 90045-47-9)
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not listed in 21 CFR prohibited/restricted lists

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Stem tissue phytochemical profile may differ from leaf; require supplier CoA with gymnemic acid and saponin quantification; reproductive flags from parent species data apply.

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Concern Level: Moderate

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Gymnema Sylvestre Stem Extract safe in cosmetics?

Stem tissue phytochemical profile may differ from leaf; require supplier CoA with gymnemic acid and saponin quantification; reproductive flags from parent species data apply. The EU classifies Gymnema Sylvestre Stem Extract as "permitted". Safety rating: MODERATE.

Is Gymnema Sylvestre Stem Extract allowed in the EU?

Gymnema Sylvestre Stem Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Gymnema Sylvestre Stem Extract do in cosmetics?

Gymnema Sylvestre Stem Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned (parent: 90045-47-9).

What is the Margin of Safety for Gymnema Sylvestre Stem Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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