HC Blue No. 18

INCI: HC BLUE NO. 18

CAS Number
1166834-57-6 / 852356-91-3
Function
Hair dyeing — azo-type direct dye for oxidative and non-oxidative formulations
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status prohibited
EU Max Conc. 0.35%
🇺🇸 US Status permitted
US Notes Permitted under coal tar hair dye exemption (21 CFR 740.2).

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Moderate sensitizer with allergic reaction risk; impurity 3B detected at 575 nm showed no genotoxic concern per SCCS; purity specifications must be controlled.

⚠️
Concern Level: High

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is HC Blue No. 18 safe in cosmetics?

Moderate sensitizer with allergic reaction risk; impurity 3B detected at 575 nm showed no genotoxic concern per SCCS; purity specifications must be controlled. The EU classifies HC Blue No. 18 as "prohibited". Safety rating: GOOD.

Is HC Blue No. 18 allowed in the EU?

HC Blue No. 18 EU regulatory status: prohibited. Maximum allowed concentration: 0.35%. This is based on EU Regulation 1223/2009 and its amendments.

What does HC Blue No. 18 do in cosmetics?

HC Blue No. 18 functions as: Hair dyeing — azo-type direct dye for oxidative and non-oxidative formulations. It is classified as a cosmetic ingredient in our database. CAS number: 1166834-57-6 / 852356-91-3.

What is the Margin of Safety for HC Blue No. 18?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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