NOAEL Studies Cosmetic Ingredient

HC Green No. 1 NOAEL Studies

CAS: 52136-25-1

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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SCCNFP Opinion 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
SCCNFP Opinion NOAEL =100 mg/kg bw/day rat dermal Sub-chronic repeated dose toxicity Ref. : 5 2, p.7
SCCNFP Opinion NOAEL =100.7 % human dermal - dermal absorption p.15
SCCNFP Opinion NOAEL =300 mg/kg bw/day rat dermal Sub-chronic repeated dose toxicity Ref. : 5 2, p.7
SCCNFP Opinion NOAEL =1000 mg/kg bw/day rat - - dermal absorption Ref. : 11 2, p.9
Regulatory source 5 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
Regulatory source dermal absorption 100.7 % human dermal - dermal absorption p.15
Regulatory source dermal absorption 1000 mg/kg bw/day rat - - dermal absorption p.9
Regulatory source irritation 100 mg/kg bw/day rat oral 13-week irritation p.15
Regulatory source repeated dose toxicity 100 mg/kg bw/day rat dermal Sub-chronic repeated dose toxicity p.7
Regulatory source repeated dose toxicity 300 mg/kg bw/day rat dermal Sub-chronic repeated dose toxicity p.7
openFDA substances 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 578544UDFJ UNII - - - chemical -