NOAEL Studies Cosmetic Ingredient

HC Red No. 13 NOAEL Studies

INCI: HC RED NO. 13

CAS: 94158-13-1

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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COSMOS DB 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
COSMOS DB LOAEL 75 mg/kg bw/day rat oral 90 day Subchronic SCCS; Weide, J.; Three-month toxicity test in rats with the test substance Kardinalrot (Part1); WELLA AG; 1985
SCCS Opinion 13 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
SCCS Opinion NOAEL =5 mg/kg bw rat - 90-day dermal absorption p.5
SCCS Opinion NOAEL =30 mg/kg bw rat - 90-day dermal absorption p.5
SCCS Opinion NOAEL =300 mg/kg/day rat oral 13 weeks NOAEL study p.21
SCCS Opinion NOAEL =84 % rat oral 13 weeks NOAEL study p.22
SCCS Opinion NOAEL =300 mg/kg bw rat oral 90-day reproductive toxicity Ref.: 22), p.30
SCCS Opinion NOAEL =30 mg/kg rat oral - NOAEL study p.30
SCCS Opinion NOAEL =4.2 mg/kg bw/day rat dermal 90-day reproductive toxicity p.33
SCCS Opinion NOAEL =300 mg/kg bw/day rat dermal 90-day reproductive toxicity p.33
SCCS Opinion NOAEL =10 - rat - - NOAEL study p.21
SCCS Opinion NOAEL =5 mg/kg bw/day - - 34 days repeated dose toxicity p.22
SCCS Opinion NOAEL =0.011 mg/kg bw/d rat oral 90 day dermal absorption p.32
SCCS Opinion NOAEL =4.2 mg/kg bw/d rat oral 90 day dermal absorption p.32
SCCS Opinion NOAEL =0.01 mg/kg bw/d rat oral 90 day dermal absorption p.33
Regulatory source 21 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
Regulatory source - 300 mg/kg/day rat oral 13 weeks - p.21
Regulatory source - 84 % rat oral 13 weeks - p.22
Regulatory source - 30 mg/kg rat oral - - p.30
Regulatory source - 300 mg/kg bw rat - - - p.31
Regulatory source - 300 mg/kg bw/day rat oral 13 weeks - p.21
Regulatory source - 10 - rat - - - p.21
Regulatory source - 30 mg/kg bw/day rat oral - - p.30
Regulatory source - 300 mg/kg bw/day rat - - - p.31
Regulatory source dermal absorption 5 mg/kg bw rat - 90-day dermal absorption p.5
Regulatory source dermal absorption 30 mg/kg bw rat - 90-day dermal absorption p.5
Regulatory source dermal absorption =0.011 mg/kg bw/d rat oral 90 day dermal absorption p.32
Regulatory source dermal absorption =4.2 mg/kg bw/d rat oral 90 day dermal absorption p.32
Regulatory source dermal absorption =0.01 mg/kg bw/d rat oral 90 day dermal absorption p.33
Regulatory source repeated dose toxicity 5 mg/kg bw/day - - 34 days repeated dose toxicity p.22
Regulatory source reproductive toxicity 300 mg/kg bw rat oral 90-day reproductive toxicity p.30
Regulatory source reproductive toxicity 4.2 mg/kg bw/day rat dermal 90-day reproductive toxicity p.33
Regulatory source reproductive toxicity 300 mg/kg bw/day rat dermal 90-day reproductive toxicity p.33
Regulatory source reproductive toxicity 300 mg/kg bw/day - - 90-day reproductive toxicity p.29
Regulatory source reproductive toxicity 5 mg/kg bw/day rat dermal - reproductive toxicity p.33
Regulatory source reproductive toxicity 4.2 mg/kg bw/day rat dermal - reproductive toxicity p.33
Regulatory source reproductive toxicity 300 mg/kg bw/day rat dermal - reproductive toxicity p.33
openFDA substances 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 3S057K0K0B UNII - - - chemical -