Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for HC Red No. 13. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| LOAEL | 75 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
Sensitization Profile
Contact sensitization data for HC Red No. 13 based on clinical patch test studies and IFRA standards.
Source: SCCS; IVDK
Expert Verdict
Potential skin sensitizer. As a nitroaniline derivative, it carries the standard concern for nitrosamine formation and should not be combined with nitrosating systems. Purity specifications require control of impurities.. Bis-hydroxyethyl amino group improves aqueous solubility and hair fiber affinity. Supplied commercially by specialty dye manufacturers such as DKSH.
Regulatory Flags
Frequently Asked Questions
Is HC Red No. 13 safe in cosmetics?
Potential skin sensitizer. As a nitroaniline derivative, it carries the standard concern for nitrosamine formation and should not be combined with nitrosating systems. Purity specifications require control of impurities.. Bis-hydroxyethyl amino group improves aqueous solubility and hair fiber affinity. Supplied commercially by specialty dye manufacturers such as DKSH. The EU classifies HC Red No. 13 as "restricted". Safety rating: MODERATE. 1 toxicological study endpoint(s) are available in our database.
Is HC Red No. 13 allowed in the EU?
HC Red No. 13 EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does HC Red No. 13 do in cosmetics?
HC Red No. 13 functions as: Hair dyeing - semi-permanent direct dye providing red to reddish-brown tones. It is classified as a cosmetic ingredient in our database. CAS number: 94158-13-1.
What is the Margin of Safety for HC Red No. 13?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for HC Red No. 13?
The NOAEL (No Observed Adverse Effect Level) for HC Red No. 13 is 75 mg/kg bw/day based on a Subchronic study via oral route in rat. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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