Is HC Red No. 13 safe in cosmetics?
HC Red No. 13 has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted.
HC Red No. 13
Also known as: EINECS 303-083-4, UNII-3S057K0K0B
INCI: HC RED NO. 13
HC Red No. 13 (CAS 94158-13-1) is a cosmetic cosmetic ingredient functioning as Hair dyeing - semi-permanent direct dye providing red to reddish-brown tones. EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 94158-13-1 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
HC Red No. 13 is classified GHS Danger (H317, H302, H315, H319, H335, H372) in the chemicals database but is restricted in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Hair dyeing - semi-permanent direct dye providing red to reddish-brown tones
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
2-[4-amino-N-(2-hydroxyethyl)-3-nitroanilino]ethanol;hydrochloride
InChIKey
ASAQRGCLIPUSEK-UHFFFAOYSA-N
Regulatory Status
EU EU Status
restricted
US US Status
permitted
US Notes
Allowed under the coal tar hair dye exemption. Must bear the statutory caution labeling and patch-test instructions.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for HC Red No. 13.
Calculate MoS for your specific formulation with the MoS Calculator.
Sensitization Profile
Contact sensitization data for HC Red No. 13 based on clinical patch test studies and IFRA standards.
Sensitization Rate
low
Allergen Class
dye
EU Allergen Listed
no
Patch Test Positive Rate
0.2%
Cross-reactivity Group
para-amino-group
Reaction Type
contact-dermatitis
Source: SCCS; IVDK
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| KR | prohibited | - | - |
Additional Ingredient Properties
2 property records from structured ingredient metadata.
allergen_detail
{"eu_allergen_listed": "no", "allergen_class": "dye", "cross_reactivity_group": "para-amino-group", "patch_test_frequency_pct": "0.2", "sensitization_rate": "low", "common_reaction_type": "contact-dermatitis", "ifra_restricted": "no", "source": "SCCS; IVDK"}
hair_dye
{"cas_number": "94158-13-1", "ingredient_class": "direct_dye", "chemical_class": "nitro", "molecular_weight_Da": "236.22", "color_result_on_hair": "Red", "shade_range": "red", "primary_function": "direct_deposit", "requires_developer": "no", "lift_capability_levels": "0", "deposit_only": "yes", "permanence": "semi_permanent", "wash_fastness_shampoos": "6-12", "light_fastness": "moderate", "heat_st…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Expert Verdict
Expert safety assessment and concern-level summary for HC Red No. 13.
Regulatory Flags
potential-allergen
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to HC Red No. 13 by CAS number or substance name.
Studies
44
Lowest NOAEL
0.01
Highest NOAEL
300
Units vary across source rows: mg/kg bw, mg/kg/day, mg/kg
SCCS_vision_codex
Known Synonyms
EINECS 303-083-4
UNII-3S057K0K0B
Chemical Function
Dye
Regulatory Lists
Canada; Personal care; Substances in PCP - Canada (4/2014)
Australian Status
AICIS status: listed
Frequently Asked Questions
Is HC Red No. 13 allowed in the EU?
HC Red No. 13 EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does HC Red No. 13 do in cosmetics?
HC Red No. 13 functions as: Hair dyeing - semi-permanent direct dye providing red to reddish-brown tones. It is classified as a cosmetic ingredient in our database. CAS number: 94158-13-1.
Is HC Red No. 13 used outside cosmetics?
HC Red No. 13 also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does HC Red No. 13 have different safety status in cosmetics vs industrial chemicals?
HC Red No. 13 is classified GHS Danger (H317, H302, H315, H319, H335, H372) in the chemicals database but is restricted in EU cosmetics.
Compliance Tools
Check HC Red No. 13 compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
Acid Blue 9
Excellent
Same category
Colorant, Hair Dyeing
Acid Blue 9 Aluminum Lake
Excellent
Same category
Colorant
Anthocyanins
Excellent
Same category
Colorant
Beta Vulgaris Extract
Excellent
Same category
Skin Conditioning, Colorant (betalain...
Beta Vulgaris Root Extract
Excellent
Same category
Skin Conditioning, Colorant (betanin/...
Beta Vulgaris Root Powder
Excellent
Same category
Skin conditioning, natural colorant, ...
(20S)-Protopanaxadiol
Moderate
Similar safety
(Cnidium Officinale/Coptis Chinensis/Glycyrrhiza Uralensis) Root Extract
Moderate
Similar safety
Skin conditioning
(Cryptomeria Japonica/Chamaecyparis Obtusa) Stem Ferment Extract
Moderate
Similar safety
Antimicrobial, antioxidant, humectant
(Eclipta Prostrata/Houttuynia Cordata) Leaf Extract
Moderate
Similar safety
Skin conditioning
(Lepidium Meyenii/Sarcodon Aspratus) Root Water
Moderate
Similar safety
Skin conditioning
(Licorice/Reynoutria Japonica) Root/Stem Extract
Moderate
Similar safety
Skin conditioning, antioxidant
Hydroxyethyl-3,4-Methylenedioxyaniline HCl
Good
Chemical family
Oxidative hair dye precursor (coupler)
HC Blue No. 10
Moderate
Browse nearby
Hair dyeing (direct / semi-permanent ...
HC Blue No. 11
Moderate
Browse nearby
Hair dyeing (direct/semi-permanent ni...
Is HC Red No. 13 in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for HC Red No. 13 in your formulation.