NOAEL Studies
Cosmetic Ingredient
HC Red No. 7 NOAEL Studies
INCI: HC RED NO. 7
CAS: 24905-87-1
Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.
CIR Safety Assessment 2 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| CIR Safety Assessment | NOAEL | =50 | mg/kg day | rat | oral | subchronic | repeated dose toxicity | 1; 7; 98, p.1 |
| CIR Safety Assessment | NOAEL | =200 | mg/kg/day | rat | oral | subchronic | repeated dose toxicity | 0; 10; 7, p.1 |
COSMOS DB 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| COSMOS DB | LOAEL | 50 | mg/kg bw/day | rat | oral | 90 day | Subchronic | SCCNFP; S.A. Brownlie. Imexine FZ: 13 Week oral (Gavage) Toxicity Study in the Rat. ToxicolLaboratories Limited Study No. LRL/25/93, |
SCCNFP Opinion 3 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| SCCNFP Opinion | NOAEL | =10 | % | rat | oral | 13-week | NOAEL study | p.17 |
| SCCNFP Opinion | NOAEL | =50 | mg/kg bw/day | rat | dermal | Sub-chronic | repeated dose toxicity | Ref. : 5 2, p.7 |
| SCCNFP Opinion | NOAEL | =200 | mg/kg bw/day | - | - | - | NOAEL study | p.17 |
Regulatory source 7 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| Regulatory source | repeated dose toxicity | 50 | mg/kg day | rat | oral | subchronic | repeated dose toxicity | p.1 |
| Regulatory source | repeated dose toxicity | 200 | mg/kg/day | rat | oral | subchronic | repeated dose toxicity | p.1 |
| Regulatory source | - | 10 | % | rat | oral | 13-week | - | p.17 |
| Regulatory source | - | 50 | mg/kg bw/day | - | - | - | - | p.10 |
| Regulatory source | - | 50 | mg/kg bw/day | rat | - | - | - | p.17 |
| Regulatory source | - | 200 | mg/kg bw/day | - | - | - | - | p.17 |
| Regulatory source | repeated dose toxicity | 50 | mg/kg bw/day | rat | dermal | Sub-chronic | repeated dose toxicity | p.7 |
openFDA substances 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| openFDA substances | FDA UNII substance identifier | 5WRI22G12X | UNII | - | - | - | chemical | - |