Also known as: HC Red 7, EINECS 246-521-9, UNII-5WRI22G12X
INCI: HC RED NO. 7
HC Red No. 7 (CAS 24905-87-1) is a cosmetic cosmetic ingredient functioning as Semi-permanent (direct) hair colorant. Reported NOAEL =50 mg/kg day in rat (CIR Safety Assessment); EU Regulation 1223/2009 status: prohibited; 3 safety opinions reviewed (CIR Safety Assessment). Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 24905-87-1 →
HC Red No. 7 is prohibited in EU cosmetics but has active industrial GHS classifications (H317, H302, H315, H319, H335).
Source: Cosmetics: ingredients.eu status; Chemicals: ghs classifications.signal word/hazard statement code
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Margin of Safety, dermal absorption, and sensitization profile summaries for HC Red No. 7.
Calculate MoS for your specific formulation with the MoS Calculator.
10 study endpoints found for HC Red No. 7. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =50 mg/kg day | oral | rat | repeated dose toxicity | CIR Safety Assessment |
| NOAEL | =50 mg/kg day | oral | rat | repeated dose toxicity | CIR Safety Assessment |
| NOAEL | =50 mg/kg day | oral | rat | repeated dose toxicity | CIR Safety Assessment |
| NOAEL | =50 mg/kg day | oral | rat | repeated dose toxicity | CIR Safety Assessment |
| NOAEL | =200 mg/kg/day | oral | rat | repeated dose toxicity | CIR Safety Assessment |
| NOAEL | =200 mg/kg/day | oral | rat | repeated dose toxicity | CIR Safety Assessment |
| NOAEL | =200 mg/kg/day | oral | rat | repeated dose toxicity | CIR Safety Assessment |
| NOAEL | =200 mg/kg/day | oral | rat | repeated dose toxicity | CIR Safety Assessment |
| NOAEL | =50 mg/kg bw/day | dermal | rat | repeated dose toxicity | SCCNFP Opinion |
| NOAEL | =50 mg/kg bw/day | dermal | rat | repeated dose toxicity | SCCNFP Opinion |
Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).
Contact sensitization data for HC Red No. 7 based on clinical patch test studies and IFRA standards.
Source: SCCS; IVDK
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| CN | permitted_hair_dye | 1 | Non-oxidative hair dye |
| BR | permitted_hair_dye | - | Direct hair dye |
Preliminary editorial summary for HC Red No. 7 — not a computed safety verdict. See the sourced toxicological data above.
Public NOAEL study rows linked to HC Red No. 7 by CAS number or substance name.
Units vary across source rows: mg/kg day, mg/kg bw/day, mg/kg/day
HC Red No. 7 has a safety rating of "GOOD" in our database. EU status: prohibited. US status: permitted. 10 toxicological study endpoint(s) are available in our database. This ingredient has been reviewed by CIR Safety Assessment.
HC Red No. 7 EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
HC Red No. 7 functions as: Semi-permanent (direct) hair colorant. It is classified as a cosmetic ingredient in our database. CAS number: 24905-87-1.
The NOAEL (No Observed Adverse Effect Level) for HC Red No. 7 is =50 mg/kg day based on a repeated dose toxicity study via oral route in rat. A total of 10 study endpoints are available. Source: CIR Safety Assessment.
HC Red No. 7 also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
HC Red No. 7 is prohibited in EU cosmetics but has active industrial GHS classifications (H317, H302, H315, H319, H335).
Check HC Red No. 7 compliance across multiple jurisdictions:
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