NOAEL Studies Cosmetic Ingredient

HC Violet No. 2 NOAEL Studies

INCI: HC VIOLET NO. 2

CAS: 104226-19-9

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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COSMOS DB 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
COSMOS DB LOAEL 50 mg/kg bw/day rat oral 90 day Subchronic SCCP; M.N. Hopkins. Imexine FAG: 13-week oral (gavage) toxicity study in the rat. Toxicol Laboratories, Report N° LRL/80/94, 1995
SCCS Opinion 3 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
SCCS Opinion NOAEL =50 mg/kg bw/d - - - NOAEL study p.14
SCCS Opinion NOAEL =2500 mg/kg bw/d human oral - NOAEL study p.20
SCCS Opinion NOAEL =50 mg/kg bw rat oral 90-day dermal absorption p.21
Regulatory source 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
Regulatory source - 50 mg/kg bw/d - - - - p.14
Regulatory source - 2500 mg/kg bw/d human oral - - p.20
Regulatory source dermal absorption =50 mg/kg bw rat oral 90-day dermal absorption p.21
Regulatory source dermal absorption 50 mg/kg bw/d mouse dermal - dermal absorption p.21
openFDA substances 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 639H4QR04O UNII - - - chemical -