NOAEL Studies Cosmetic Ingredient

HC Yellow No. 13 NOAEL Studies

INCI: HC YELLOW NO. 13

CAS: 10442-83-8

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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COSMOS DB 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
COSMOS DB LOAEL 10 mg/kg bw/day rat oral 91 day Subchronic SCCS; 90-Day toxicity study with "Fluorgelb II" in rats. Hruby, 1991
SCCNFP Opinion 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
SCCNFP Opinion NOAEL =2.5 % rat dermal developmental developmental toxicity Ref. : 13 2, p.11
SCCNFP Opinion NOAEL =30 mg/kg rabbit dermal Sub-chronic repeated dose toxicity Ref. : 9 2, p.7
SCCNFP Opinion NOAEL =90 mg/kg bw - - - reproductive toxicity p.10
SCCNFP Opinion NOAEL =90 mg/kg rat oral 90-day developmental toxicity p.17
Regulatory source 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
Regulatory source developmental toxicity 2.5 % rat dermal developmental developmental toxicity p.11
Regulatory source developmental toxicity 90 mg/kg rat oral 90-day developmental toxicity p.17
Regulatory source repeated dose toxicity 30 mg/kg rabbit dermal Sub-chronic repeated dose toxicity p.7
Regulatory source reproductive toxicity 90 mg/kg bw - - - reproductive toxicity p.10
openFDA substances 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 0448DT2KKS UNII - - - chemical -