NOAEL Studies Cosmetic Ingredient

HC Yellow No. 7 NOAEL Studies

INCI: HC YELLOW NO. 7

CAS: 104226-21-3

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

Back to parent ingredient page
COSMOS DB 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
COSMOS DB LOAEL 10 mg/kg bw/day rat oral 90 day Subchronic SCCS; C. Fabreguettes. Imexine AA: 13 Week Toxicity Study by oral Route in Rats. CIT Study No. 11390 TCR
SCCNFP Opinion 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
SCCNFP Opinion NOAEL =25 mg/kg bw/day - oral Sub-chronic repeated dose toxicity Ref. : 5 2, p.7
SCCNFP Opinion NOAEL =80 mg/kg bw/day - oral Sub-chronic repeated dose toxicity Ref. : 5 2, p.7
Regulatory source 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
Regulatory source dermal absorption 25 mg/kg bw/day human - - dermal absorption p.11
Regulatory source irritation 25 mg/kg bw/day rat oral 4-week irritation p.16
Regulatory source repeated dose toxicity 25 mg/kg bw/day - oral Sub-chronic repeated dose toxicity p.7
Regulatory source repeated dose toxicity 80 mg/kg bw/day - oral Sub-chronic repeated dose toxicity p.7
openFDA substances 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 6L0860JBFE UNII - - - chemical -