Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for HC Yellow No. 7. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| LOAEL | 10 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
Expert Verdict
Prohibited in EU but permitted in US under coal-tar hair dye exemption; moderate safety profile with narrow safety margin at 0.25% maximum concentration.
Regulatory Flags
Frequently Asked Questions
Is HC Yellow No. 7 safe in cosmetics?
Prohibited in EU but permitted in US under coal-tar hair dye exemption; moderate safety profile with narrow safety margin at 0.25% maximum concentration. The EU classifies HC Yellow No. 7 as "prohibited". Safety rating: MODERATE. 1 toxicological study endpoint(s) are available in our database.
Is HC Yellow No. 7 allowed in the EU?
HC Yellow No. 7 EU regulatory status: prohibited. Maximum allowed concentration: 0.25%. This is based on EU Regulation 1223/2009 and its amendments.
What does HC Yellow No. 7 do in cosmetics?
HC Yellow No. 7 functions as: Hair Dyeing (non-oxidative semi-permanent). It is classified as a cosmetic ingredient in our database. CAS number: 104226-21-3.
What is the Margin of Safety for HC Yellow No. 7?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for HC Yellow No. 7?
The NOAEL (No Observed Adverse Effect Level) for HC Yellow No. 7 is 10 mg/kg bw/day based on a Subchronic study via oral route in rat. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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