Is Hexamidine safe in cosmetics?
Hexamidine has a safety rating of "GOOD" in our database. EU status: restricted. US status: permitted.
GOOD
Cosmetic Ingredient
Hexamidine
INCI: HEXAMIDINE
Hexamidine (CAS 3811-75-4) is a cosmetic cosmetic ingredient functioning as Preservative / antimicrobial (biocide). EU Regulation 1223/2009 status: restricted, max 0.1%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
Function
Preservative / antimicrobial (biocide)
Editorial assessment
GOOD
Preliminary editorial note — not a computed safety verdict.
Chemistry & Identifiers
IUPAC Name
4-[6-(4-carbamimidoylphenoxy)hexoxy]benzenecarboximidamide
InChIKey
OQLKNTOKMBVBKV-UHFFFAOYSA-N
Regulatory Status
EU EU Status
restricted
EU Max Conc.
0.1%
US US Status
permitted
US Notes
Permitted — no specific CFR restriction; CIR assessed as safe as used
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Hexamidine.
Calculate MoS for your specific formulation with the MoS Calculator.
Editorial summary
Preliminary editorial summary for Hexamidine — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
preservative
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
HEXAMIDINE
ChEMBL ID
CHEMBL25105
Max Phase
2
Frequently Asked Questions
Is Hexamidine allowed in the EU?
Hexamidine EU regulatory status: restricted. Maximum allowed concentration: 0.1%. This is based on EU Regulation 1223/2009 and its amendments.
What does Hexamidine do in cosmetics?
Hexamidine functions as: Preservative / antimicrobial (biocide). It is classified as a cosmetic ingredient in our database. CAS number: 3811-75-4.
Is Hexamidine used outside cosmetics?
Hexamidine also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Hexamidine compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Is Hexamidine in Your Products?
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Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Hexamidine in your formulation.