Homarine HCl

INCI: HOMARINE HCL

CAS Number
824-84-0 (N-methylpicolinic acid hydrochloride)
Function
Humectant, Skin Conditioning — protects skin cells from dehydration and environmental stress
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — not restricted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Limited independent toxicological data; safety supported primarily by supplier data and structural analogy to other marine osmolytes. Strengthens skin barrier function. CPSR assessor should request supplier tox dossier.

⚠️
Concern Level: Moderate

Frequently Asked Questions

Is Homarine HCl safe in cosmetics?

Limited independent toxicological data; safety supported primarily by supplier data and structural analogy to other marine osmolytes. Strengthens skin barrier function. CPSR assessor should request supplier tox dossier. The EU classifies Homarine HCl as "permitted". Safety rating: GOOD.

Is Homarine HCl allowed in the EU?

Homarine HCl EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Homarine HCl do in cosmetics?

Homarine HCl functions as: Humectant, Skin Conditioning — protects skin cells from dehydration and environmental stress. It is classified as a cosmetic ingredient in our database. CAS number: 824-84-0 (N-methylpicolinic acid hydrochloride).

What is the Margin of Safety for Homarine HCl?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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