Is Homosalate safe in cosmetics?
Homosalate has a safety rating of "MODERATE" in our database. EU status: restricted. US status: restricted.
Moderate
Active Ingredient
Homosalate
INCI: HOMOSALATE
Homosalate (CAS 118-56-9) is a cosmetic active ingredient functioning as Oil-soluble UVB UV filter; peak absorption ~306 nm; used as SPF booster in. EU Regulation 1223/2009 status: restricted, max 7.34%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 118-56-9 →
Auto-generated CPSR Part A draft with source citations
Function
Oil-soluble UVB UV filter; peak absorption ~306 nm; used as SPF booster in combination formulations; UVB-only spectrum with no UVA coverage
Safety Rating
MODERATE
Regulatory Status
EU EU Status
restricted
EU Max Conc.
7.34%
US US Status
restricted
US Notes
Historically marketed in the US; FDA states existing data is not sufficient to determine GRASE. Regulatory limbo alongside seven other chemical filters. Final determination pending additional safety data. Previously permitted up to 15% in the US monograph.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Homosalate.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Homosalate.
Regulatory Flags
uv-filter
uvb
oil-soluble
fda-limbo
systemic-absorption
endocrine-disruption-concern
eu-restricted
eu-face-only
spf-booster
regulatory-downgrade-2025
product-withdrawal-july-2025
ifra_fragrance
eu_cosing_listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
HOMOSALATE
ChEMBL ID
CHEMBL1377575
Max Phase
2
Adverse Event Associations
95
Frequently Asked Questions
Is Homosalate allowed in the EU?
Homosalate EU regulatory status: restricted. Maximum allowed concentration: 7.34%. This is based on EU Regulation 1223/2009 and its amendments.
What does Homosalate do in cosmetics?
Homosalate functions as: Oil-soluble UVB UV filter; peak absorption ~306 nm; used as SPF booster in combination formulations; UVB-only spectrum with no UVA coverage. It is classified as a Active Ingredient in our database. CAS number: 118-56-9.
Is Homosalate used outside cosmetics?
Homosalate also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Homosalate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Is Homosalate in Your Products?
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Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Homosalate in your formulation.