Hydrogenated Cottonseed Glyceride

INCI: HYDROGENATED COTTONSEED GLYCERIDE

CAS Number
| 6
Function
Skin conditioning—occlusive, surfactant, viscosity increasing agent
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — CIR Expert Panel concluded safe as used (originally 2001, re-reviewed 2022); not restricted under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Hydrogenated cottonseed glyceride is permitted for cosmetic use with adequate safety margins. However, raw cottonseed oil may contain gossypol, aflatoxin, and cyclopropenoid fatty acids (CPFA), which are toxic. Cosmetic-grade material must be refined to eliminate these contaminants. Require supplier CoA confirming gossypol below limit of detection and aflatoxin compliance.

⚠️
Concern Level: Moderate

Frequently Asked Questions

Is Hydrogenated Cottonseed Glyceride safe in cosmetics?

Hydrogenated cottonseed glyceride is permitted for cosmetic use with adequate safety margins. However, raw cottonseed oil may contain gossypol, aflatoxin, and cyclopropenoid fatty acids (CPFA), which are toxic. Cosmetic-grade material must be refined to eliminate these contaminants. Require supplier CoA confirming gossypol below limit of detection and aflatoxin compliance. The EU classifies Hydrogenated Cottonseed Glyceride as "permitted". Safety rating: GOOD.

Is Hydrogenated Cottonseed Glyceride allowed in the EU?

Hydrogenated Cottonseed Glyceride EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydrogenated Cottonseed Glyceride do in cosmetics?

Hydrogenated Cottonseed Glyceride functions as: Skin conditioning—occlusive, surfactant, viscosity increasing agent. It is classified as a cosmetic ingredient in our database. CAS number: | 6.

What is the Margin of Safety for Hydrogenated Cottonseed Glyceride?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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