Good Cosmetic Ingredient NOAEL Data GHS Classified

HYDROCHLOROFLUOROCARBON 142B

CAS Number
75-68-3
Function
Deodorant, Propellant
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status Permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status Not specifically regulated

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Toxicological Studies

3 study endpoints found for HYDROCHLOROFLUOROCARBON 142B. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL >20000 ppm 1991 rat inhalation REACH
NOAEL >10000 ppm 1991 rat inhalation REACH
NOAEL >10000 ppm 1991 dog inhalation REACH

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
Rapid evaporation of the liquid may cause frostbite. The substance may cause effects on the cardiovascular system.
Routes of Exposure
The substance can be absorbed into the body by inhalation.

Expert Verdict

HYDROCHLOROFLUOROCARBON 142B is listed in the EU CosIng database with functions: Deodorant, Propellant It is permitted in the EU without specific restrictions.

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Concern Level: Low

Regulatory Flags

cosing-sourced eu-permitted needs-enrichment

Frequently Asked Questions

Is HYDROCHLOROFLUOROCARBON 142B safe in cosmetics?

HYDROCHLOROFLUOROCARBON 142B is listed in the EU CosIng database with functions: Deodorant, Propellant It is permitted in the EU without specific restrictions. The EU classifies HYDROCHLOROFLUOROCARBON 142B as "Permitted". Safety rating: GOOD. 3 toxicological study endpoint(s) are available in our database.

Is HYDROCHLOROFLUOROCARBON 142B allowed in the EU?

HYDROCHLOROFLUOROCARBON 142B EU regulatory status: Permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does HYDROCHLOROFLUOROCARBON 142B do in cosmetics?

HYDROCHLOROFLUOROCARBON 142B functions as: Deodorant, Propellant. It is classified as a cosmetic ingredient in our database. CAS number: 75-68-3.

What is the NOAEL for HYDROCHLOROFLUOROCARBON 142B?

The NOAEL (No Observed Adverse Effect Level) for HYDROCHLOROFLUOROCARBON 142B is >20000 ppm based on a inhalation study via 1991 route in rat. A total of 3 study endpoints are available. Source: REACH.

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