Hydrolyzed Spinal Protein

INCI: HYDROLYZED SPINAL PROTEIN

CAS Number
Not uniquely assigned
Function
Skin conditioning, hair conditioning
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes Permitted with restrictions. FDA BSE guidance recommends against use of CNS tissue from cattle in cosmetics (FDA Guidance for Industry, 2004). No explicit CFR prohibition but strong regulatory advisory.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

RED FLAG: BSE/TSE risk. Spinal cord is specified risk material (SRM) in cattle over 12 months. If bovine-derived, effectively banned in EU and strongly discouraged in US. Species of origin must be documented. Porcine or fish-derived spinal protein would avoid BSE concern but still requires full safety dossier. No CIR review or standalone toxicological data available. A CPSR assessor would reject without: species origin certificate, TSE certificate of suitability (CEP from EDQM or equivalent), and complete toxicological package.

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Concern Level: High

Frequently Asked Questions

Is Hydrolyzed Spinal Protein safe in cosmetics?

RED FLAG: BSE/TSE risk. Spinal cord is specified risk material (SRM) in cattle over 12 months. If bovine-derived, effectively banned in EU and strongly discouraged in US. Species of origin must be documented. Porcine or fish-derived spinal protein would avoid BSE concern but still requires full safety dossier. No CIR review or standalone toxicological data available. A CPSR assessor would reject without: species origin certificate, TSE certificate of suitability (CEP from EDQM or equivalent), and complete toxicological package. The EU classifies Hydrolyzed Spinal Protein as "prohibited". Safety rating: POOR.

Is Hydrolyzed Spinal Protein allowed in the EU?

Hydrolyzed Spinal Protein EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydrolyzed Spinal Protein do in cosmetics?

Hydrolyzed Spinal Protein functions as: Skin conditioning, hair conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not uniquely assigned.

What is the Margin of Safety for Hydrolyzed Spinal Protein?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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