Hydrolyzed Wheat Gluten Extract

INCI: HYDROLYZED WHEAT GLUTEN

CAS Number
100684-25-1 (Hydrolyzed Wheat Gluten)
Function
Hair conditioning agent; skin conditioning agent
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted with conditions. CIR concluded safe only when formulated to restrict peptides to weight-average MW โ‰ค3,500 Da (CIR 2018 final report).

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Hydrolyzed wheat gluten extract is permitted in cosmetics as a conditioning agent, but must be formulated to restrict peptide weight-average molecular weight to โ‰ค3,500 Da to maintain safety.

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Hydrolyzed Wheat Gluten Extract safe in cosmetics?

Hydrolyzed wheat gluten extract is permitted in cosmetics as a conditioning agent, but must be formulated to restrict peptide weight-average molecular weight to โ‰ค3,500 Da to maintain safety. The EU classifies Hydrolyzed Wheat Gluten Extract as "permitted". Safety rating: MODERATE.

Is Hydrolyzed Wheat Gluten Extract allowed in the EU?

Hydrolyzed Wheat Gluten Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydrolyzed Wheat Gluten Extract do in cosmetics?

Hydrolyzed Wheat Gluten Extract functions as: Hair conditioning agent; skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 100684-25-1 (Hydrolyzed Wheat Gluten).

What is the Margin of Safety for Hydrolyzed Wheat Gluten Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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