NOAEL Studies Cosmetic Ingredient

Hydroxyanthraquinoneaminopropyl Methyl Morpholinium Methosulfate NOAEL Studies

INCI: HYDROXYANTHRAQUINONEAMINOPROPYL METHYL MORPHOLINIUM METHOSULFATE

CAS: 38866-20-5

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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COSMOS DB 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
COSMOS DB LOAEL 200 mg/kg bw/day rat oral 90 day Subchronic SCCP; C. Fabreguettes. 13-Week Toxicity Studyby Oral Route in Rats. CIT Study No. 12417TCR (95/2/002), November 6, 1995
COSMOS DB NOAEL 50 mg/kg bw/day rat oral 90 day Subchronic SCCP; C. Fabreguettes. 13-Week Toxicity Studyby Oral Route in Rats. CIT Study No. 12417TCR (95/2/002), November 6, 1995
SCCS Opinion 7 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
SCCS Opinion NOAEL =0.015 mg/kg bw/d rat oral 13-week dermal absorption p.28
SCCS Opinion NOAEL =26 mg/kg bw/d human - - NOAEL study p.27
SCCS Opinion NOAEL =50 mg/kg bw/d - - Chronic genotoxicity p.17
SCCS Opinion NOAEL =87.5 % rat oral 13 week dermal absorption p.19
SCCS Opinion NOAEL =200 mg/kg bw/d - - Chronic genotoxicity p.14
SCCS Opinion NOAEL =200 mg/kg rat oral 13 week dermal absorption p.19
SCCS Opinion NOAEL =800 mg/kg bw/d human - - NOAEL study p.18
Regulatory source 10 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
Regulatory source - 26 mg/kg bw/d human - - - p.27
Regulatory source - 800 mg/kg bw/d human - - - p.18
Regulatory source dermal absorption =0.015 mg/kg bw/d rat oral 13-week dermal absorption p.28
Regulatory source dermal absorption =50 mg/kg bw/d rat oral 13-week dermal absorption p.28
Regulatory source dermal absorption 87.5 % rat oral 13 week dermal absorption p.19
Regulatory source dermal absorption =200 mg/kg rat oral 13 week dermal absorption p.19
Regulatory source genotoxicity 50 mg/kg bw/d - - Chronic genotoxicity p.17
Regulatory source genotoxicity 200 mg/kg bw/d - - Chronic genotoxicity p.14
Regulatory source repeated dose toxicity 50 mg/kg bw/d rat oral 13 week repeated dose toxicity p.28
Regulatory source repeated dose toxicity 200 mg/kg bw/d rat oral 13 week repeated dose toxicity p.19
openFDA substances 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier RNJ1LHE5O7 UNII - - - chemical -