Hydroxyethyl-2,6-Dinitro-p-Anisidine

INCI: HYDROXYETHYL-2,6-DINITRO-P-ANISIDINE

CAS Number
122252-11-3
Function
Hair dye substance (direct/semi-permanent)
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted with coal tar hair dye exemption under 21 CFR 73/74 (caution labeling and patch test required per FD&C Act Section 601)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Prohibited in EU due to insufficient toxicological data and genotoxicity/mutagenicity concerns from dinitroaniline structural class; do not formulate for EU/EEA/UK markets. Permitted in US under coal tar hair dye exemption with required caution labeling and patch testing.

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Concern Level: High

Regulatory Flags

eu_banned_cosmetics eu_cosing_listed

Frequently Asked Questions

Is Hydroxyethyl-2,6-Dinitro-p-Anisidine safe in cosmetics?

Prohibited in EU due to insufficient toxicological data and genotoxicity/mutagenicity concerns from dinitroaniline structural class; do not formulate for EU/EEA/UK markets. Permitted in US under coal tar hair dye exemption with required caution labeling and patch testing. The EU classifies Hydroxyethyl-2,6-Dinitro-p-Anisidine as "prohibited". Safety rating: POOR.

Is Hydroxyethyl-2,6-Dinitro-p-Anisidine allowed in the EU?

Hydroxyethyl-2,6-Dinitro-p-Anisidine EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydroxyethyl-2,6-Dinitro-p-Anisidine do in cosmetics?

Hydroxyethyl-2,6-Dinitro-p-Anisidine functions as: Hair dye substance (direct/semi-permanent). It is classified as a cosmetic ingredient in our database. CAS number: 122252-11-3.

What is the Margin of Safety for Hydroxyethyl-2,6-Dinitro-p-Anisidine?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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