Hydroxyethyl Diphenyl Imidazoline

INCI: HYDROXYETHYL DIPHENYL IMIDAZOLINE

CAS Number
Not confirmed via standard databases for this specific INCI
Function
Antistatic agent
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not restricted under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

RED FLAG. Australian AICIS evaluation of hydroxyethyl imidazoline class found evidence of skin necrosis and irreversible eye damage in rabbit studies. Diphenyl variant may differ but structural alert remains. Requires HRIPT, ocular irritation testing, and full tox package before use. Not recommended without comprehensive safety data

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Concern Level: High

Frequently Asked Questions

Is Hydroxyethyl Diphenyl Imidazoline safe in cosmetics?

RED FLAG. Australian AICIS evaluation of hydroxyethyl imidazoline class found evidence of skin necrosis and irreversible eye damage in rabbit studies. Diphenyl variant may differ but structural alert remains. Requires HRIPT, ocular irritation testing, and full tox package before use. Not recommended without comprehensive safety data The EU classifies Hydroxyethyl Diphenyl Imidazoline as "permitted". Safety rating: POOR.

Is Hydroxyethyl Diphenyl Imidazoline allowed in the EU?

Hydroxyethyl Diphenyl Imidazoline EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydroxyethyl Diphenyl Imidazoline do in cosmetics?

Hydroxyethyl Diphenyl Imidazoline functions as: Antistatic agent. It is classified as a cosmetic ingredient in our database. CAS number: Not confirmed via standard databases for this specific INCI.

What is the Margin of Safety for Hydroxyethyl Diphenyl Imidazoline?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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