Hydroxyisoleucine
Regulatory Status
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Safety Data
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Expert Verdict
Neat compound carries GHS skin and eye irritant classifications; diluted cosmetic use likely safe but lacks published dermal toxicity and sensitization data at cosmetic concentrations. Primarily studied as a nutraceutical insulin sensitizer rather than topical ingredient.
Regulatory Flags
Frequently Asked Questions
Is Hydroxyisoleucine safe in cosmetics?
Neat compound carries GHS skin and eye irritant classifications; diluted cosmetic use likely safe but lacks published dermal toxicity and sensitization data at cosmetic concentrations. Primarily studied as a nutraceutical insulin sensitizer rather than topical ingredient. The EU classifies Hydroxyisoleucine as "permitted". Safety rating: MODERATE.
Is Hydroxyisoleucine allowed in the EU?
Hydroxyisoleucine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hydroxyisoleucine do in cosmetics?
Hydroxyisoleucine functions as: Humectant; Softener and conditioner. It is classified as a cosmetic ingredient in our database. CAS number: 55399-93-4 (racemic); L-4-Hydroxyisoleucine: 781658-23-9.
What is the Margin of Safety for Hydroxyisoleucine?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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