Hydroxylated Docosahexaenoic Acid

INCI: HYDROXYLATED DOCOSAHEXAENOIC ACID

CAS Number
Multiple isomers exist (e.g., 11-HDHA: 87018-59-5); no single CAS assigned for the cosmetic INCI
Function
Skin conditioning, antioxidant, anti-inflammatory
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not prohibited or restricted under 21 CFR; parent DHA (6217-54-5) has GRAS status for food use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Highly oxidation-prone polyunsaturated compound requiring inert atmosphere storage; peroxide value must be controlled; limited published cosmetic safety dossier.

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Concern Level: Moderate

Frequently Asked Questions

Is Hydroxylated Docosahexaenoic Acid safe in cosmetics?

Highly oxidation-prone polyunsaturated compound requiring inert atmosphere storage; peroxide value must be controlled; limited published cosmetic safety dossier. The EU classifies Hydroxylated Docosahexaenoic Acid as "permitted". Safety rating: MODERATE.

Is Hydroxylated Docosahexaenoic Acid allowed in the EU?

Hydroxylated Docosahexaenoic Acid EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydroxylated Docosahexaenoic Acid do in cosmetics?

Hydroxylated Docosahexaenoic Acid functions as: Skin conditioning, antioxidant, anti-inflammatory. It is classified as a cosmetic ingredient in our database. CAS number: Multiple isomers exist (e.g., 11-HDHA: 87018-59-5); no single CAS assigned for the cosmetic INCI.

What is the Margin of Safety for Hydroxylated Docosahexaenoic Acid?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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