Hydroxylauroyl Phytosphingosine

INCI: HYDROXYLAUROYL PHYTOSPHINGOSINE

CAS Number
Verify via CosIng / CIR ceramides report — multiple ceramide CAS numbers exist (e.g., 100403-19-8 shared across ceramide subtypes)
Function
Skin conditioning agent (ceramide / skin-identical lipid)
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted - not restricted under 21 CFR; CIR reviewed

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Phytosphingosine base shows serious eye damage (H318) and aquatic toxicity (H400/H410) hazards in ECHA notifications; eye area formulations require specific irritation testing and environmental discharge considerations.

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Concern Level: Moderate

Frequently Asked Questions

Is Hydroxylauroyl Phytosphingosine safe in cosmetics?

Phytosphingosine base shows serious eye damage (H318) and aquatic toxicity (H400/H410) hazards in ECHA notifications; eye area formulations require specific irritation testing and environmental discharge considerations. The EU classifies Hydroxylauroyl Phytosphingosine as "permitted". Safety rating: GOOD.

Is Hydroxylauroyl Phytosphingosine allowed in the EU?

Hydroxylauroyl Phytosphingosine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydroxylauroyl Phytosphingosine do in cosmetics?

Hydroxylauroyl Phytosphingosine functions as: Skin conditioning agent (ceramide / skin-identical lipid). It is classified as a cosmetic ingredient in our database. CAS number: Verify via CosIng / CIR ceramides report — multiple ceramide CAS numbers exist (e.g., 100403-19-8 shared across ceramide subtypes).

What is the Margin of Safety for Hydroxylauroyl Phytosphingosine?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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