Hydroxymethoxyphenyl Propylmethylmethoxybenzofuran

INCI: HYDROXYMETHOXYPHENYL PROPYLMETHYLMETHOXYBENZOFURAN

CAS Number
NOT IDENTIFIED — no public CAS registry match found
Function
Skin conditioning agent (structurally suggests neolignan/benzofuran derivative)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Regulatory status not confirmed. No PCPC/INCI listing or CFR status identified.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Critical data gap: no publicly available toxicological data, no confirmed CAS number, and no regulatory status identified. Benzofuran scaffold requires mandatory genotoxicity and mutagenicity assessment. Cannot be included in a CPSR without complete manufacturer-supplied safety dossier. Minimum required testing: Ames test, in-vitro chromosomal aberration, 90-day repeat-dose oral study, dermal absorption study, and HRIPT.

⚠️
Concern Level: High

Frequently Asked Questions

Is Hydroxymethoxyphenyl Propylmethylmethoxybenzofuran safe in cosmetics?

Critical data gap: no publicly available toxicological data, no confirmed CAS number, and no regulatory status identified. Benzofuran scaffold requires mandatory genotoxicity and mutagenicity assessment. Cannot be included in a CPSR without complete manufacturer-supplied safety dossier. Minimum required testing: Ames test, in-vitro chromosomal aberration, 90-day repeat-dose oral study, dermal absorption study, and HRIPT. The EU classifies Hydroxymethoxyphenyl Propylmethylmethoxybenzofuran as "permitted". Safety rating: MODERATE.

Is Hydroxymethoxyphenyl Propylmethylmethoxybenzofuran allowed in the EU?

Hydroxymethoxyphenyl Propylmethylmethoxybenzofuran EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydroxymethoxyphenyl Propylmethylmethoxybenzofuran do in cosmetics?

Hydroxymethoxyphenyl Propylmethylmethoxybenzofuran functions as: Skin conditioning agent (structurally suggests neolignan/benzofuran derivative). It is classified as a cosmetic ingredient in our database. CAS number: NOT IDENTIFIED — no public CAS registry match found.

What is the Margin of Safety for Hydroxymethoxyphenyl Propylmethylmethoxybenzofuran?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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