Regulatory Status
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Safety Data
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Expert Verdict
Highest phytoestrogen concern among all Medicago sativa parts. Sprouts contain significantly elevated levels of coumestrol and other phytoestrogenic compounds (liquiritigenin, isoliquiritigenin, loliolide) that show strong transactivation of ERα (up to 80% of 17β-estradiol) and ERβ. Requires careful risk assessment for estrogenic activity in leave-on products.. Germination increases polyphenol content and antioxidant activity, which typically peak around days 5-7 of sprouting. Used in some fo...
Regulatory Flags
Frequently Asked Questions
Is Medicago Sativa Sprout Extract safe in cosmetics?
Highest phytoestrogen concern among all Medicago sativa parts. Sprouts contain significantly elevated levels of coumestrol and other phytoestrogenic compounds (liquiritigenin, isoliquiritigenin, loliolide) that show strong transactivation of ERα (up to 80% of 17β-estradiol) and ERβ. Requires careful risk assessment for estrogenic activity in leave-on products.. Germination increases polyphenol content and antioxidant activity, which typically peak around days 5-7 of sprouting. Used in some fo... The EU classifies Medicago Sativa Sprout Extract as "permitted". Safety rating: MODERATE.
Is Medicago Sativa Sprout Extract allowed in the EU?
Medicago Sativa Sprout Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Medicago Sativa Sprout Extract do in cosmetics?
Medicago Sativa Sprout Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned in CosIng.
What is the Margin of Safety for Medicago Sativa Sprout Extract?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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