Hydroxypropyl Methylcellulose Acetate Succinate

INCI: HYDROXYPROPYL METHYLCELLULOSE ACETATE SUCCINATE

CAS Number
71138-97-1
Function
Film-forming agent
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR safe as used; FDA GRAS (GRN 960) for food. Parent polymer HPMC approved as ophthalmic demulcent in OTC.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

CIR-approved safe cellulose derivative with no EU Annex restrictions. Primarily a pharmaceutical excipient with niche cosmetic use as a pH-sensitive film former.

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Concern Level: Low

Frequently Asked Questions

Is Hydroxypropyl Methylcellulose Acetate Succinate safe in cosmetics?

CIR-approved safe cellulose derivative with no EU Annex restrictions. Primarily a pharmaceutical excipient with niche cosmetic use as a pH-sensitive film former. The EU classifies Hydroxypropyl Methylcellulose Acetate Succinate as "permitted". Safety rating: GOOD.

Is Hydroxypropyl Methylcellulose Acetate Succinate allowed in the EU?

Hydroxypropyl Methylcellulose Acetate Succinate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydroxypropyl Methylcellulose Acetate Succinate do in cosmetics?

Hydroxypropyl Methylcellulose Acetate Succinate functions as: Film-forming agent. It is classified as a cosmetic ingredient in our database. CAS number: 71138-97-1.

What is the Margin of Safety for Hydroxypropyl Methylcellulose Acetate Succinate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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