Nylon-6/12

INCI: NYLON-6/12

CAS Number
25191-04-2
Function
Bulking Agent, Opacifying, Absorbent, Texturizer
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FDA-approved indirect food additive (21 CFR 177.1500). CIR 2015: safe in present practices.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Toxicologically benign with oral LD50 >10 g/kg, 0% sensitization in HRIPT at 1.4%, and negative genotoxicity. Major compliance issue: EU REACH microplastics ban applies with phased deadlines for leave-on products; verify exemption criteria or reformulate.

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Concern Level: None

Regulatory Flags

NEW_REGULATION

Frequently Asked Questions

Is Nylon-6/12 safe in cosmetics?

Toxicologically benign with oral LD50 >10 g/kg, 0% sensitization in HRIPT at 1.4%, and negative genotoxicity. Major compliance issue: EU REACH microplastics ban applies with phased deadlines for leave-on products; verify exemption criteria or reformulate. The EU classifies Nylon-6/12 as "permitted". Safety rating: EXCELLENT.

Is Nylon-6/12 allowed in the EU?

Nylon-6/12 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Nylon-6/12 do in cosmetics?

Nylon-6/12 functions as: Bulking Agent, Opacifying, Absorbent, Texturizer. It is classified as a cosmetic ingredient in our database. CAS number: 25191-04-2.

What is the Margin of Safety for Nylon-6/12?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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