Hydroxypropyl Starch Phosphate
INCI: HYDROXYPROPYL STARCH PHOSPHATE
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
6 study endpoints found for Hydroxypropyl Starch Phosphate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 2500 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 25500 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 12500 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 82500 mg/kg bw/day | oral | mouse | Chronic | COSMOS_DB |
| NOAEL | 82500 mg/kg bw/day | oral | mouse | Chronic | COSMOS_DB |
| NOAEL | 82500 mg/kg bw/day | oral | mouse | Carcinogenicity | COSMOS_DB |
Expert Verdict
Very clean modified starch ingredient; CIR safe as used (2022), not mutagenic (Ames), no carcinogenicity evidence.
Regulatory Flags
Frequently Asked Questions
Is Hydroxypropyl Starch Phosphate safe in cosmetics?
Very clean modified starch ingredient; CIR safe as used (2022), not mutagenic (Ames), no carcinogenicity evidence. The EU classifies Hydroxypropyl Starch Phosphate as "permitted". Safety rating: GOOD. 6 toxicological study endpoint(s) are available in our database.
Is Hydroxypropyl Starch Phosphate allowed in the EU?
Hydroxypropyl Starch Phosphate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hydroxypropyl Starch Phosphate do in cosmetics?
Hydroxypropyl Starch Phosphate functions as: Viscosity controlling agent, bulking agent, thickener. It is classified as a cosmetic ingredient in our database. CAS number: 53124-00-8.
What is the Margin of Safety for Hydroxypropyl Starch Phosphate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Hydroxypropyl Starch Phosphate?
The NOAEL (No Observed Adverse Effect Level) for Hydroxypropyl Starch Phosphate is 2500 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 6 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
Check Hydroxypropyl Starch Phosphate compliance across multiple jurisdictions:
Related Ingredients
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