Hydroxypropyltrimonium Corn/Wheat/Soy Amino Acids

INCI: HYDROXYPROPYLTRIMONIUM CORN/WHEAT/SOY AMINO ACIDS

CAS Number
Complex mixture — no single CAS (multi-source hydrolyzed protein derivative)
Function
Hair conditioning, anti-static, skin conditioning
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — no CFR restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Allergen risk is the primary concern. Hydrolyzed wheat proteins have been linked to serious sensitization events including contact urticaria and anaphylaxis. EU requires gluten/wheat declaration awareness. Soy is a major allergen. Molecular weight of hydrolysate should exceed 3,500 Da to reduce sensitization risk. CPSR assessor must document allergen risk assessment per SCCS guidelines.

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Concern Level: High

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Hydroxypropyltrimonium Corn/Wheat/Soy Amino Acids safe in cosmetics?

Allergen risk is the primary concern. Hydrolyzed wheat proteins have been linked to serious sensitization events including contact urticaria and anaphylaxis. EU requires gluten/wheat declaration awareness. Soy is a major allergen. Molecular weight of hydrolysate should exceed 3,500 Da to reduce sensitization risk. CPSR assessor must document allergen risk assessment per SCCS guidelines. The EU classifies Hydroxypropyltrimonium Corn/Wheat/Soy Amino Acids as "permitted". Safety rating: MODERATE.

Is Hydroxypropyltrimonium Corn/Wheat/Soy Amino Acids allowed in the EU?

Hydroxypropyltrimonium Corn/Wheat/Soy Amino Acids EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydroxypropyltrimonium Corn/Wheat/Soy Amino Acids do in cosmetics?

Hydroxypropyltrimonium Corn/Wheat/Soy Amino Acids functions as: Hair conditioning, anti-static, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Complex mixture — no single CAS (multi-source hydrolyzed protein derivative).

What is the Margin of Safety for Hydroxypropyltrimonium Corn/Wheat/Soy Amino Acids?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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