Hydroxypropyltrimonium Hydrolyzed Keratin

INCI: HYDROXYPROPYLTRIMONIUM HYDROLYZED KERATIN

CAS Number
Not individually assigned (parent Hydrolyzed Keratin CAS: 65997-21-9 / 73049-73-7) [^1_10]
Function
Antistatic, hair conditioning, skin conditioning
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” 21 CFR ยง700.27 does not prohibit keratin from hooves/horns; CIR concluded all 8 keratin-derived ingredients safe (2016)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Animal-derived ingredient with robust safety data; ensure BSE-free certification and non-human-hair sourcing for EU compliance; rare case reports of IgE reactivity in highly sensitized individuals.

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Concern Level: Low

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Hydroxypropyltrimonium Hydrolyzed Keratin safe in cosmetics?

Animal-derived ingredient with robust safety data; ensure BSE-free certification and non-human-hair sourcing for EU compliance; rare case reports of IgE reactivity in highly sensitized individuals. The EU classifies Hydroxypropyltrimonium Hydrolyzed Keratin as "permitted". Safety rating: EXCELLENT.

Is Hydroxypropyltrimonium Hydrolyzed Keratin allowed in the EU?

Hydroxypropyltrimonium Hydrolyzed Keratin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydroxypropyltrimonium Hydrolyzed Keratin do in cosmetics?

Hydroxypropyltrimonium Hydrolyzed Keratin functions as: Antistatic, hair conditioning, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not individually assigned (parent Hydrolyzed Keratin CAS: 65997-21-9 / 73049-73-7) [^1_10].

What is the Margin of Safety for Hydroxypropyltrimonium Hydrolyzed Keratin?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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