Hydroxypropyltrimonium Hydrolyzed Rice Protein/Siloxysilicate

INCI: HYDROXYPROPYLTRIMONIUM HYDROLYZED RICE PROTEIN/SILOXYSILICATE

CAS Number
Not assigned (complex copolymer; no single CAS)
Function
Hair conditioning (protein-silicone hybrid film-former)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no CFR restriction; not prohibited or restricted under 21 CFR Parts 250/700

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Limited independent toxicological data on the specific copolymer; relies on read-across from hydrolyzed rice protein and silicone safety profiles; ensure silicone portion is free of D4/D5 cyclomethicone contamination per EU Regulation 2018/35

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Concern Level: Moderate

Frequently Asked Questions

Is Hydroxypropyltrimonium Hydrolyzed Rice Protein/Siloxysilicate safe in cosmetics?

Limited independent toxicological data on the specific copolymer; relies on read-across from hydrolyzed rice protein and silicone safety profiles; ensure silicone portion is free of D4/D5 cyclomethicone contamination per EU Regulation 2018/35 The EU classifies Hydroxypropyltrimonium Hydrolyzed Rice Protein/Siloxysilicate as "permitted". Safety rating: GOOD.

Is Hydroxypropyltrimonium Hydrolyzed Rice Protein/Siloxysilicate allowed in the EU?

Hydroxypropyltrimonium Hydrolyzed Rice Protein/Siloxysilicate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydroxypropyltrimonium Hydrolyzed Rice Protein/Siloxysilicate do in cosmetics?

Hydroxypropyltrimonium Hydrolyzed Rice Protein/Siloxysilicate functions as: Hair conditioning (protein-silicone hybrid film-former). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (complex copolymer; no single CAS).

What is the Margin of Safety for Hydroxypropyltrimonium Hydrolyzed Rice Protein/Siloxysilicate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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