Is Cetethyl Morpholinium Ethosulfate safe in cosmetics?
Cetethyl Morpholinium Ethosulfate has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted. This ingredient has been reviewed by CIR Safety Assessment.
Cetethyl Morpholinium Ethosulfate
Also known as: Morpholinium, 4-ethyl-4-hexadecyl-, ethyl sulfate (1:1), G 251, Atlas G 263, Barquat cme-A, Caswell No. 165F (+12 more)
INCI: CETETHYL MORPHOLINIUM ETHOSULFATE
Cetethyl Morpholinium Ethosulfate (CAS 78-21-7) is a cosmetic cosmetic ingredient functioning as Antistatic, Hair Conditioning. EU Regulation 1223/2009 status: permitted; 1 safety opinion reviewed (CIR Safety Assessment). Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 78-21-7 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Cetethyl Morpholinium Ethosulfate is classified GHS Danger (H302, H318) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu status; Chemicals: ghs classifications.signal word/hazard statement code
Function
Antistatic, Hair Conditioning
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
4-ethyl-4-hexadecylmorpholin-4-ium;ethyl sulfate
InChIKey
QDQHWKZZJJDBND-UHFFFAOYSA-M
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not restricted; limited CIR data available
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Cetethyl Morpholinium Ethosulfate.
Calculate MoS for your specific formulation with the MoS Calculator.
Safety Opinions
Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).
CIR Safety Assessment
15 May 2001
Verdict: unknown
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Anti-static agent
Biocide
Emulsifier
Softener and conditioner
Surfactant (surface active agent)
Regulatory List Membership (1)
FDA Indirect Food Contact Additives
Expert Verdict
Expert safety assessment and concern-level summary for Cetethyl Morpholinium Ethosulfate.
Known Synonyms
Morpholinium, 4-ethyl-4-hexadecyl-, ethyl sulfate (1:1)
G 251
Atlas G 263
Barquat cme-A
Caswell No. 165F
Morpholinium, 4-ethyl-4-hexadecyl-, ethyl sulfate
N-Cetyl-N-ethylmorpholinium ethosulfate
N-Cetyl-N-ethylmorpholinium ethyl sulfate
N-Cetyl-N-ethylmorpholinium ethylsulfate
EINECS 201-094-8
EPA Pesticide Chemical Code 069187
4-Ethyl-4-hexadecyl morpholinium ethyl sulfate
Ethyl-N-hexadecylmorpholinium ethosulfate
N-Hexadecyl-N-ethylmorpholinium ethyl sulfate
NSC 215231
Sulfuric acid, monoethyl ester, ion(1-), 4-ethyl-4-hexadecylmorpholinium
UNII-FU19SYM476
Chemical Function
Surfactant (surface active agent)
Biocide
Anti-static agent
Emulsifier
Softener and conditioner
Regulatory Lists
CEDI
Indirect additives food contact (10/2018)
Frequently Asked Questions
Is Cetethyl Morpholinium Ethosulfate allowed in the EU?
Cetethyl Morpholinium Ethosulfate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Cetethyl Morpholinium Ethosulfate do in cosmetics?
Cetethyl Morpholinium Ethosulfate functions as: Antistatic, Hair Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 78-21-7.
Is Cetethyl Morpholinium Ethosulfate used outside cosmetics?
Cetethyl Morpholinium Ethosulfate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Cetethyl Morpholinium Ethosulfate have different safety status in cosmetics vs industrial chemicals?
Cetethyl Morpholinium Ethosulfate is classified GHS Danger (H302, H318) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Cetethyl Morpholinium Ethosulfate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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