Hydroxypropyltrimonium Hydrolyzed Wheat Protein

INCI: HYDROXYPROPYLTRIMONIUM HYDROLYZED WHEAT PROTEIN

CAS Number
Not uniquely assigned (polymeric; EINECS not listed)
Function
Antistatic, hair conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” CIR concluded safe when peptide MW โ‰ค 3500 Da (weight-average)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

MW specification is mandatory โ€” supplier CoA must confirm weight-average MW โ‰ค 3500 Da. SCCS/1534/14 documents anaphylaxis cases from high-MW hydrolyzed wheat in facial soaps in Japan. Gluten/wheat allergen labeling required in many jurisdictions. CPSR assessor will flag this ingredient without MW documentation.

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Hydroxypropyltrimonium Hydrolyzed Wheat Protein safe in cosmetics?

MW specification is mandatory โ€” supplier CoA must confirm weight-average MW โ‰ค 3500 Da. SCCS/1534/14 documents anaphylaxis cases from high-MW hydrolyzed wheat in facial soaps in Japan. Gluten/wheat allergen labeling required in many jurisdictions. CPSR assessor will flag this ingredient without MW documentation. The EU classifies Hydroxypropyltrimonium Hydrolyzed Wheat Protein as "permitted". Safety rating: MODERATE.

Is Hydroxypropyltrimonium Hydrolyzed Wheat Protein allowed in the EU?

Hydroxypropyltrimonium Hydrolyzed Wheat Protein EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydroxypropyltrimonium Hydrolyzed Wheat Protein do in cosmetics?

Hydroxypropyltrimonium Hydrolyzed Wheat Protein functions as: Antistatic, hair conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not uniquely assigned (polymeric; EINECS not listed).

What is the Margin of Safety for Hydroxypropyltrimonium Hydrolyzed Wheat Protein?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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