Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Classified H302 (harmful if swallowed), H315, H320 per GHS. As a serotonin precursor, systemic exposure via dermal route is a theoretical concern at high concentrations. Topical cosmetic use data is sparse — supplier tox pack essential for CPSR.
Frequently Asked Questions
Is Hydroxytryptophan safe in cosmetics?
Classified H302 (harmful if swallowed), H315, H320 per GHS. As a serotonin precursor, systemic exposure via dermal route is a theoretical concern at high concentrations. Topical cosmetic use data is sparse — supplier tox pack essential for CPSR. The EU classifies Hydroxytryptophan as "permitted". Safety rating: MODERATE.
Is Hydroxytryptophan allowed in the EU?
Hydroxytryptophan EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hydroxytryptophan do in cosmetics?
Hydroxytryptophan functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 56-69-9 [^1_7].
What is the Margin of Safety for Hydroxytryptophan?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
Check Hydroxytryptophan compliance across multiple jurisdictions:
Related Ingredients
Is Hydroxytryptophan in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Hydroxytryptophan in your formulation.