Hypericum Perforatum Flower/Leaf Extract

CAS Number
84082-80-4 / EC 282-026-4 [^1_8]
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted under CIR 2013 Amended Safety Assessment; however, no reported uses or concentration of use data at time of CIR review

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

No reported cosmetic uses at time of CIR review; assessor may require additional concentration-of-use data due to hypericin phototoxicity potential.

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Concern Level: Moderate

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Hypericum Perforatum Flower/Leaf Extract safe in cosmetics?

No reported cosmetic uses at time of CIR review; assessor may require additional concentration-of-use data due to hypericin phototoxicity potential. The EU classifies Hypericum Perforatum Flower/Leaf Extract as "permitted". Safety rating: GOOD.

Is Hypericum Perforatum Flower/Leaf Extract allowed in the EU?

Hypericum Perforatum Flower/Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What is the Margin of Safety for Hypericum Perforatum Flower/Leaf Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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