Imiloxan HCl

INCI: IMILOXAN HCL

CAS Number
81167-22-8 (HCl salt)
Function
Highly selective α₂B-adrenoceptor antagonist
Safety Rating
POOR

Regulatory Status

🇪🇺 EU Status prohibited
🇺🇸 US Status prohibited
US Notes Not listed for cosmetic use. A cosmetic making drug claims or containing pharmacologically active substances falls under FDA drug regulation (21 CFR 201).

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Imiloxan HCl is a pharmaceutical research compound not approved for cosmetic use; formulation into cosmetics risks regulatory reclassification as an unauthorized medicinal product in both EU and US without full toxicological dossier and regulatory legal opinion.

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Concern Level: High

Frequently Asked Questions

Is Imiloxan HCl safe in cosmetics?

Imiloxan HCl is a pharmaceutical research compound not approved for cosmetic use; formulation into cosmetics risks regulatory reclassification as an unauthorized medicinal product in both EU and US without full toxicological dossier and regulatory legal opinion. The EU classifies Imiloxan HCl as "prohibited". Safety rating: POOR.

Is Imiloxan HCl allowed in the EU?

Imiloxan HCl EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Imiloxan HCl do in cosmetics?

Imiloxan HCl functions as: Highly selective α₂B-adrenoceptor antagonist. It is classified as a cosmetic ingredient in our database. CAS number: 81167-22-8 (HCl salt).

What is the Margin of Safety for Imiloxan HCl?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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