Good Cosmetic Ingredient

Tetrasodium Hydroxy Iminodisuccinate

INCI: TETRASODIUM HYDROXY IMINODISUCCINATE

CAS Number
190195-65-4 (related: Tetrasodium Iminodisuccinate 144538-83-0)
Function
Chelating Agent
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted under general provisions; CIR reviewed related iminodisuccinate ingredients — safe as used

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Biodegradable EDTA alternative with favorable environmental profile; readily biodegradable; limited independent safety data but structurally well-characterized

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Concern Level: Low

Frequently Asked Questions

Is Tetrasodium Hydroxy Iminodisuccinate safe in cosmetics?

Biodegradable EDTA alternative with favorable environmental profile; readily biodegradable; limited independent safety data but structurally well-characterized The EU classifies Tetrasodium Hydroxy Iminodisuccinate as "permitted". Safety rating: GOOD.

Is Tetrasodium Hydroxy Iminodisuccinate allowed in the EU?

Tetrasodium Hydroxy Iminodisuccinate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Tetrasodium Hydroxy Iminodisuccinate do in cosmetics?

Tetrasodium Hydroxy Iminodisuccinate functions as: Chelating Agent. It is classified as a cosmetic ingredient in our database. CAS number: 190195-65-4 (related: Tetrasodium Iminodisuccinate 144538-83-0).

What is the Margin of Safety for Tetrasodium Hydroxy Iminodisuccinate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Tetrasodium Hydroxy Iminodisuccinate compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
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