NOAEL Studies Cosmetic Ingredient

Isobutyl Methacrylate NOAEL Studies

INCI: ISOBUTYL METHACRYLATE

CAS: 97-86-9

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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NTP_ICE_acute_oral 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP_ICE_acute_oral LD50 =9590 mg/kg bw Rat oral acute Rat Acute Oral Toxicity NLM Hazardous Substances Data Bank (undated); record_id=acute_oral_11856; row=5817; data_type=In Vivo; mixture=Chemical; chemical_name=Isobutyl methacrylate; preferred_name=Isobutyl methacrylate; dtxsid=DTXSID3025461; url=https://pubchem.ncbi.nlm.nih.gov/; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3025461; url_cebs=https://doi.org/10.22427/NTP-DATA-DTXSID3025461; source_file=acute_oral.xlsx
ToxValDB_GESTIS_DNEL 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_GESTIS_DNEL DNEL local =409 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL_dup_-_15632832_15632833:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_4829c722f6aecf2e949fa120c8b5b274
ToxValDB_GESTIS_DNEL DNEL systemic =415.9 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL_dup_-_15632832_15632833:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_70f77254e4ce06280e6cab3f96859e2c
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier V11534UYZ0 UNII - - - chemical {"approval_status":null,"molecular_formula":"C8H14O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"V11534UYZ0"}
openFDA substances FDA UNII substance identifier V11534UYZ0 UNII - - - chemical {"approval_status":null,"molecular_formula":"C8H14O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"V11534UYZ0"}
openFDA substances FDA UNII substance identifier V11534UYZ0 UNII - - - chemical {"approval_status":null,"molecular_formula":"C8H14O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"V11534UYZ0"}
openFDA substances FDA UNII substance identifier V11534UYZ0 UNII - - - chemical {"approval_status":null,"molecular_formula":"C8H14O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"V11534UYZ0"}